منابع مشابه
Retraining the injured spinal cord.
The present review presents a series of concepts that may be useful in developing rehabilitative strategies to enhance recovery of posture and locomotion following spinal cord injury. First, the loss of supraspinal input results in a marked change in the functional efficacy of the remaining synapses and neurons of intraspinal and peripheral afferent (dorsal root ganglion) origin. Second, follow...
متن کاملSpinal Cord-Injured Rats
Opérant conditioning of the spinal stretch reflex or its electrical analog, the H-reflex, is a new model for exploring the mechanisms of long-term supraspinal control over spinal cord function. Primates and rats can gradually increase (HRup conditioning mode) or decrease (HRdown conditioning mode) the H-reflex when reward is based on H-reflex amplitude. An earlier study indicated that HRdown co...
متن کاملMatrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord.
In the injured spinal cord, a glial scar forms and becomes a major obstacle to axonal regeneration. Formation of the glial scar involves migration of astrocytes toward the lesion. Matrix metalloproteinases (MMPs), including MMP-9 and MMP-2, govern cell migration through their ability to degrade constituents of the extracellular matrix. Although MMP-9 is expressed in reactive astrocytes, its inv...
متن کاملTopical Review Retraining the injured spinal cord
reorganization of the sensorimotor pathways occurs caudal to the lesion. Some of these changes are inevitable just from the loss of some or all descending fibres. Synapses on the membranes of interneurones, motoneurones and, perhaps, propriospinal neurones may change in number, size and distribution. Any of these alterations can contribute to changes in the efficacy of neuronal input. Even with...
متن کاملTracheostomy in Spinal Cord Injured Patients
Patients with cervical spinal cord injury frequently need prolonged mechanical ventilation as a result of worsening pulmonary vital capacity due to paralysis of respiratory muscles, severe impairment of tracheobronchial secretions clearance and high incidence of respiratory complications like pneumonia or atelectasis. Patients with thoracic spinal cord injury may need mechanical ventilation due...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurosurgery
سال: 2014
ISSN: 0148-396X
DOI: 10.1227/01.neu.0000442977.99453.a2